A volunteer model for the comparison of laxatives in opioid-related constipation

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15 صفحه اول

Laxatives Do Not Improve Symptoms of Opioid-Induced Constipation: Results of a Patient Survey.

Introduction Laxatives are commonly used to treat opioid-induced constipation, the commonest and most bothersome complication of opioids. However, laxatives have a nonspecific action and do not target underlying mechanisms of opioid-induced constipation; their use is associated with abdominal symptoms that negatively impact quality of life. Objective To assess the effects of laxatives in pati...

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Methylnaltrexone or laxatives for the Management of Opioid-induced Constipation among Palliative Patients on Opioid Therapy: Evidence-based Review

Constipation is a common symptom in advanced cancer patients. Studies have demonstrated that 40 to 80% of patients on a palliative care service have constipation. This proportion increases to ≥ 90% when patients are treated with opioids [1-5]. Fredericks, Hollis and Stricker, [6-10] defines constipation as less than three defecations per week (or change from usual pattern), or the subjective sy...

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Therapy for chronic constipation with plant laxatives

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ژورنال

عنوان ژورنال: Journal of Pain and Symptom Management

سال: 1996

ISSN: 0885-3924

DOI: 10.1016/0885-3924(96)00011-5